A bizarre experiment funded by the Bill & Melinda Gates Foundation developed a new vaccine strategy using mosquito bites as a delivery vector in pursuit of developing a “next generation” malaria vaccine.
The experiment was conducted by researchers at the Leiden University Medical Center (LUMC) in Leiden, Netherlands, and published last month in the peer-reviewed New England Journal of Medicine.
Researchers explained how they used the bites of mosquitos to deliver a short-lived malaria vaccine comprised of genetically modified malaria parasites.
“We conducted a double-blind, controlled clinical trial to evaluate the safety, side-effect profile, and efficacy of immunization, by means of mosquito bites, with a second-generation genetically attenuated parasite (GA2) — a mei2 single knockout P. falciparum NF54 parasite (sporozoite form) with extended development into the liver stage,” the researchers stated.
The Plasmodium falciparum (P. falciparum) parasite causes malaria in humans. […]
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