There was an unexpected surge in the diagnosis of Type 1 diabetes among children and teenagers worldwide amidst the global impact of the COVID-19 pandemic, according to a new study.
The systematic review, published by the Journal of the American Medical Association (JAMA), analyzed 42 studies on diabetes incidence, including 17 studies involving nearly 38,000 people under the age of 19. The review revealed a 14 percent surge in Type 1 diabetes cases in 2020, followed by a 27 percent increase in 2021, compared to before the pandemic.
Furthermore, the research highlighted a rise in Type 2 diabetes incidence and diabetic ketoacidosis, a severe complication of diabetes more common in Type 1 patients, after the start of the pandemic.
What Is the Link Between COVID and Type 1 Diabetes?
The exact connection between COVID-19 and the higher risk of developing diabetes is unclear, according to the authors of the study. However, some doctors disagree.
Type 1 diabetes is well established as an autoimmune disease, where the body attacks its own pancreatic beta cells, a primary source of insulin.
Both viral infections and vaccinations are known triggers for autoimmune diseases, and COVID-19 and its vaccine could be no exception, Dr. Paul Marik, a critical care physician, former tenured professor at Eastern Virginia Medical School, and co-founder of the Frontline COVID-19 Critical Care (FLCCC) Alliance, told The Epoch Times.
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Numerous case reports have documented instances where patients developed Type 1 diabetes following either COVID-19 infection or COVID-19 vaccination.
The spike proteins present in the SARS-CoV-2 virus, as well as those produced by the body after vaccination, are very likely to be causing autoimmunity, according to Dr. Marik.
“There is few doubts that SARS-CoV-2 spike protein is the most likely trigger of Type 1 diabetes,” Dr. Flavio Cadegiani, an endocrinologist and researcher at Federal University of São Paulo in Brazil, told The Epoch Times via email.
The primary role of COVID-19 spike proteins is to attach to ACE-2 receptors on cell surfaces and enter the cells. Pancreatic beta cells, which have ACE-2 receptors, are vulnerable to infection and potential damage caused by spike protein entry.
Spike proteins also share similarities with human proteins, and their presence may lead the body to produce antibodies that not only target the spike protein but also attack human tissues, including the pancreas.
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This phenomenon of molecular mimicry is seen in vaccine-injured patients, and those with long COVID, Dr. Marik said. Studies have found autoantibodies—antibodies that attack the body’s own tissues or cells—in both groups of patients.
Type 2 Diabetes: More Common and Complicated Consequence
The study may mistakenly conflate Type 1 and Type 2 diabetes as the same disease, hence the “no clear underlying mechanism” conclusion, board-certified internist Dr. Keith Berkowitz told The Epoch Times.
Type 2 diabetes, compared to Type 1, is more complex and metabolic, influenced by factors like obesity, processed food, heart disease, blood cholesterol, and hypertension.
Dr. Berkowitz said he has observed a unique blood glucose dysregulation pattern in his post-COVID and post-vaccine patients.
Patients with Type 2 diabetes typically have high blood sugar levels with high or low insulin levels as the beta cells become fatigued. However, Dr. Berkowitz said he observed that some of his patients had low blood sugar alongside high insulin levels, a condition he said he has never encountered before.
“Even my well-controlled diabetic patients are not faring well, especially those who have received both vaccinations and had COVID infections,” Dr. Berkowitz added.
Dr. Berkowitz uses intravenous fluids to address these conditions in Type 2 diabetics, restoring their water balance and blood sugar regulation. “When a diabetic goes to the hospital, the first thing they do is administer intravenous saline because insulin doesn’t work well in a severely dehydrated cell,” he said.
Treatment for Autoimmunity and Type 1 Diabetes
Autoimmunity is a condition where the body’s immune system mistakenly identifies its own cells, tissues, or organs as foreign invaders and attacks them. This can lead to various autoimmune diseases.
But the body may be brought back into balance.
1. Remove COVID-19 Spike Protein
The spike protein may contribute to autoimmune disease, prompting doctors to consider therapies that may remove these inflammatory proteins.
Research suggests that fasting can trigger autophagy, the process of clearing old, damaged, and foreign proteins.
Intermittent fasting and prolonged fasts, even for three days, may “reset” the immune system, potentially reducing autoimmune activity. Fasting, however, is not recommended for children or pregnant or breastfeeding women.
Other recommended therapies for spike protein removal include ivermectin, an antiparasitic drug, and N-acetylcysteine (NAC) supplementation.
2. Supplement With Vitamin D
Vitamin D insufficiency, a common deficiency among the U.S. population, has been linked to autoimmune disorders.
Research shows vitamin D supplementation reduces autoimmune disease risk by 22 percent. Infants given vitamin D also have lower Type 1 diabetes incidence, a 2001 study found.
Vitamin D reduces inflammation and provides infection protection. Some scientists propose it helps the immune system differentiate between self and non-self.
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Dr. Cadegiani stated that one of his first therapies is to increase Type 1 diabetes patients’ vitamin D levels between the range of 60 to 90 ng/ml, which is around 6,000 to 9,000 IUs of dietary vitamin D per day.
Vitamin D is also linked to improved insulin sensitivity.
3. Reduce Sugar Intake
Sugar contributes to inflammation, and studies have found that those who consume high levels of sugar over extended periods are at a higher risk of developing autoimmune diseases.
In the case of patients with Type 1 diabetes, Dr. Cadegiani said that cutting glucose and carbohydrate consumption reduces insulin, and, therefore, can prevent the body from forming more autoantibodies against pancreatic beta cells.
4. Hydroxychloroquine
Dr. Cadegiani said that he sometimes prescribes hydroxychloroquine when a patient is positive for Type 1 diabetes antibodies, but still has around normal blood sugar levels.
The anti-malarial drug hydroxychloroquine is a powerful drug that fights autoimmune diseases. It is able to bind to the ACE-2 receptors and prevent spike protein entry and is also able to block spike protein from causing further harm.
It is currently approved by the U.S. Food and Drug Administration (FDA) for use in chronic discoid lupus erythematosus, systemic lupus erythematosus in adults, and rheumatoid arthritis, all autoimmune diseases.
Studies have shown that hydroxychloroquine can also reduce blood sugar and is associated with a reduced risk of Type 1 diabetes. The use of chloroquine, a hydroxychloroquine derivative, in Type 1 diabetes cases can reduce inflammation in the body.
5. Plant Supplements
Plant supplements like curcumin and berberine also have anti-diabetic properties and may help prevent Type 1 diabetes.
Curcumin can decrease blood sugar and insulin levels and reduce inflammation and oxidation. Some theories have suggested that curcumin may be able to prevent the immune system from overreacting, which results in autoimmunity.
Curcumin reduces inflammation in the gut, helping with digestion and overall gut health. An unhealthy gut can lead to a dysregulated immune system, increasing the risk of autoimmunity.
Despite being a plant compound, berberine has been found to have potent blood glucose-lowering properties. Berberine has been shown to be protective against pancreatic beta cells and also improve insulin resistance.
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Thus, both patients with Type 1 or Type 2 diabetes may supplement with berberine. Those already taking medications for diabetes may need to consult their doctors before supplementing with berberine.
6. Diabetes Drugs
Dr. Cadegiani also uses diabetes drugs like metformin and liraglutide to treat and prevent Type 1 diabetes.
Metformin is a common diabetes drug that can reduce blood sugar levels. In Type 1 diabetes, metformin increases insulin sensitivity and action and also increases peripheral glucose uptake.
Liraglutide increases satiety and slows gastric emptying. Studies have also shown that the drug increases pancreatic beta cell mass, improves the cells’ functions, and prevents beta cell deaths, all of which may help prevent Type 1 diabetes.
Article cross-posted from our premium news partners at The Epoch Times.
Five Things New “Preppers” Forget When Getting Ready for Bad Times Ahead
The preparedness community is growing faster than it has in decades. Even during peak times such as Y2K, the economic downturn of 2008, and Covid, the vast majority of Americans made sure they had plenty of toilet paper but didn’t really stockpile anything else.
Things have changed. There’s a growing anxiety in this presidential election year that has prompted more Americans to get prepared for crazy events in the future. Some of it is being driven by fearmongers, but there are valid concerns with the economy, food supply, pharmaceuticals, the energy grid, and mass rioting that have pushed average Americans into “prepper” mode.
There are degrees of preparedness. One does not have to be a full-blown “doomsday prepper” living off-grid in a secure Montana bunker in order to be ahead of the curve. In many ways, preparedness isn’t about being able to perfectly handle every conceivable situation. It’s about being less dependent on government for as long as possible. Those who have proper “preps” will not be waiting for FEMA to distribute emergency supplies to the desperate masses.
Below are five things people new to preparedness (and sometimes even those with experience) often forget as they get ready. All five are common sense notions that do not rely on doomsday in order to be useful. It may be nice to own a tank during the apocalypse but there’s not much you can do with it until things get really crazy. The recommendations below can have places in the lives of average Americans whether doomsday comes or not.
Note: The information provided by this publication or any related communications is for informational purposes only and should not be considered as financial advice. We do not provide personalized investment, financial, or legal advice.
Secured Wealth
Whether in the bank or held in a retirement account, most Americans feel that their life’s savings is relatively secure. At least they did until the last couple of years when de-banking, geopolitical turmoil, and the threat of Central Bank Digital Currencies reared their ugly heads.
It behooves Americans to diversify their holdings. If there’s a triggering event or series of events that cripple the financial systems or devalue the U.S. Dollar, wealth can evaporate quickly. To hedge against potential turmoil, many Americans are looking in two directions: Crypto and physical precious metals.
There are huge advantages to cryptocurrencies, but there are also inherent risks because “virtual” money can become challenging to spend. Add in the push by central banks and governments to regulate or even replace cryptocurrencies with their own versions they control and the risks amplify. There’s nothing wrong with cryptocurrencies today but things can change rapidly.
As for physical precious metals, many Americans pay cash to keep plenty on hand in their safe. Rolling over or transferring retirement accounts into self-directed IRAs is also a popular option, but there are caveats. It can often take weeks or even months to get the gold and silver shipped if the owner chooses to close their account. This is why Genesis Gold Group stands out. Their relationship with the depositories allows for rapid closure and shipping, often in less than 10 days from the time the account holder makes their move. This can come in handy if things appear to be heading south.
Lots of Potable Water
One of the biggest shocks that hit new preppers is understanding how much potable water they need in order to survive. Experts claim one gallon of water per person per day is necessary. Even the most conservative estimates put it at over half-a-gallon. That means that for a family of four, they’ll need around 120 gallons of water to survive for a month if the taps turn off and the stores empty out.
Being near a fresh water source, whether it’s a river, lake, or well, is a best practice among experienced preppers. It’s necessary to have a water filter as well, even if the taps are still working. Many refuse to drink tap water even when there is no emergency. Berkey was our previous favorite but they’re under attack from regulators so the Alexapure systems are solid replacements.
For those in the city or away from fresh water sources, storage is the best option. This can be challenging because proper water storage containers take up a lot of room and are difficult to move if the need arises. For “bug in” situations, having a larger container that stores hundreds or even thousands of gallons is better than stacking 1-5 gallon containers. Unfortunately, they won’t be easily transportable and they can cost a lot to install.
Water is critical. If chaos erupts and water infrastructure is compromised, having a large backup supply can be lifesaving.
Pharmaceuticals and Medical Supplies
There are multiple threats specific to the medical supply chain. With Chinese and Indian imports accounting for over 90% of pharmaceutical ingredients in the United States, deteriorating relations could make it impossible to get the medicines and antibiotics many of us need.
Stocking up many prescription medications can be hard. Doctors generally do not like to prescribe large batches of drugs even if they are shelf-stable for extended periods of time. It is a best practice to ask your doctor if they can prescribe a larger amount. Today, some are sympathetic to concerns about pharmacies running out or becoming inaccessible. Tell them your concerns. It’s worth a shot. The worst they can do is say no.
If your doctor is unwilling to help you stock up on medicines, then Jase Medical is a good alternative. Through telehealth, they can prescribe daily meds or antibiotics that are shipped to your door. As proponents of medical freedom, they empathize with those who want to have enough medical supplies on hand in case things go wrong.
Energy Sources
The vast majority of Americans are locked into the grid. This has proven to be a massive liability when the grid goes down. Unfortunately, there are no inexpensive remedies.
Those living off-grid had to either spend a lot of money or effort (or both) to get their alternative energy sources like solar set up. For those who do not want to go so far, it’s still a best practice to have backup power sources. Diesel generators and portable solar panels are the two most popular, and while they’re not inexpensive they are not out of reach of most Americans who are concerned about being without power for extended periods of time.
Natural gas is another necessity for many, but that’s far more challenging to replace. Having alternatives for heating and cooking that can be powered if gas and electric grids go down is important. Have a backup for items that require power such as manual can openers. If you’re stuck eating canned foods for a while and all you have is an electric opener, you’ll have problems.
Don’t Forget the Protein
When most think about “prepping,” they think about their food supply. More Americans are turning to gardening and homesteading as ways to produce their own food. Others are working with local farmers and ranchers to purchase directly from the sources. This is a good idea whether doomsday comes or not, but it’s particularly important if the food supply chain is broken.
Most grocery stores have about one to two weeks worth of food, as do most American households. Grocers rely heavily on truckers to receive their ongoing shipments. In a crisis, the current process can fail. It behooves Americans for multiple reasons to localize their food purchases as much as possible.
Long-term storage is another popular option. Canned foods, MREs, and freeze dried meals are selling out quickly even as prices rise. But one component that is conspicuously absent in shelf-stable food is high-quality protein. Most survival food companies offer low quality “protein buckets” or cans of meat, but they are often barely edible.
Prepper All-Naturals offers premium cuts of steak that have been cooked sous vide and freeze dried to give them a 25-year shelf life. They offer Ribeye, NY Strip, and Tenderloin among others.
Having buckets of beans and rice is a good start, but keeping a solid supply of high-quality protein isn’t just healthier. It can help a family maintain normalcy through crises.
Prepare Without Fear
With all the challenges we face as Americans today, it can be emotionally draining. Citizens are scared and there’s nothing irrational about their concerns. Being prepared and making lifestyle changes to secure necessities can go a long way toward overcoming the fears that plague us. We should hope and pray for the best but prepare for the worst. And if the worst does come, then knowing we did what we could to be ready for it will help us face those challenges with confidence.
